MDR1 gene polymorphism and phenytoin pharmacokinetics in epilepsy

Adel, Alhazzani; Murali, Munisamy; Gauthaman, Karunakaran

Adel, Alhazzani; Murali, Munisamy; Gauthaman, Karunakaran.

Bahrain Medical Bulletin. 2017; 39 (1): 29-32

in English | IMEMR | ID: emr-185649

ABSTRACT

ABSTRACT

Background:

Pharmacokinetics is a widely used anti-epileptic drug phenytoin, which exhibits noticeable inter-individual variations in efficacy. Genetic factors, such as MDR1 gene polymorphism may play a crucial role in drug response

Subject(s)

Adult; Adolescent; Female; Humans; Male; Young Adult; Polymorphism, Genetic; Epilepsy/drug therapy; Genotyping Techniques; Phenytoin/pharmacokinetics; Case-Control Studies; Saudi Arabia

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Index: IMEMR (Eastern Mediterranean) Main subject: Phenytoin / Polymorphism, Genetic / Saudi Arabia / Case-Control Studies / Epilepsy / Genotyping Techniques Limits: Adolescent / Adult / Female / Humans / Male Country/Region as subject: Asia Language: English Journal: Bahrain Med. Bull. Year: 2017

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