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In silico screening and evaluation of the anticonvulsant activity of docosahexaenoic acid-like molecules in experimental models of seizures
IBJ-Iranian Biomedical Journal. 2017; 21 (1): 32-39
in English | IMEMR | ID: emr-185665
ABSTRACT

Background:

Resistance to antiepileptic drugs and the intolerability in 20-30% of the patients raises demand for developing new drugs with improved efficacy and safety. Acceptable anticonvulsant activity, good tolerability, and inexpensiveness of docosahexaenoic acid [DHA] make it as a good candidate for designing and development of the new anticonvulsant medications
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Index: IMEMR (Eastern Mediterranean) Main subject: Pentylenetetrazole / Seizures / Electroshock / Epilepsy / Models, Biological / Anticonvulsants Type of study: Screening study Limits: Animals Language: English Journal: Iran. Biomed. J. Year: 2017

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Index: IMEMR (Eastern Mediterranean) Main subject: Pentylenetetrazole / Seizures / Electroshock / Epilepsy / Models, Biological / Anticonvulsants Type of study: Screening study Limits: Animals Language: English Journal: Iran. Biomed. J. Year: 2017