In silico screening and evaluation of the anticonvulsant activity of docosahexaenoic acid-like molecules in experimental models of seizures
IBJ-Iranian Biomedical Journal. 2017; 21 (1): 32-39
in English
| IMEMR
| ID: emr-185665
ABSTRACT
Background:
Resistance to antiepileptic drugs and the intolerability in 20-30% of the patients raises demand for developing new drugs with improved efficacy and safety. Acceptable anticonvulsant activity, good tolerability, and inexpensiveness of docosahexaenoic acid [DHA] make it as a good candidate for designing and development of the new anticonvulsant medications
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Pentylenetetrazole
/
Seizures
/
Electroshock
/
Epilepsy
/
Models, Biological
/
Anticonvulsants
Type of study:
Screening study
Limits:
Animals
Language:
English
Journal:
Iran. Biomed. J.
Year:
2017
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