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Antipyretic potential of herbal coded formulation [Pyrexol]
Pakistan Journal of Pharmaceutical Sciences. 2017; 30 (1): 195-198
in English | IMEMR | ID: emr-185758
ABSTRACT
The antipyretic effect of the aqueous extract of herbal coded formulation containing equal amount of Salix alba, Emblica officinalis, Glycyrrhiza glabra, Adhatoda vasica, Viola odorata, Thea sinensis, Veleriana officinalis, Foeniculum vulgare, Sisymbrium irrio and Achillea millefolium was investigated using the yeast induced pyrexia model in rabbits. Paracetamol was used as a control group. Rectal temperatures of all rabbits were recorded immediately before the administration of the extract or paracetamol and again at 1 hour, after this, temperature was noted at 1 hrs interval for 5 hrs using digital thermometer. At 240 mg/kg dose the extract showed significant reduction in yeast-induced elevated temperature as compared with that of standard drug paracetamol [150 mg/kg]. It is concluded that herbal coded medicine at a dose of 240 mg/kg has marked antipyretic activity in animal models and this strongly supports the ethno pharmacological uses of medicinal plants of this formulation
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Index: IMEMR (Eastern Mediterranean) Main subject: Plants, Medicinal / Rabbits / Body Temperature Regulation / Antipyretics / Acetaminophen / Phytotherapy Limits: Animals Language: English Journal: Pak. J. Pharm. Sci. Year: 2017

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Index: IMEMR (Eastern Mediterranean) Main subject: Plants, Medicinal / Rabbits / Body Temperature Regulation / Antipyretics / Acetaminophen / Phytotherapy Limits: Animals Language: English Journal: Pak. J. Pharm. Sci. Year: 2017