Specific IgA antibodies to herpes simplex virus type I in duodenal juice and saliva from patients with peptic ulcer

ABSTRACT

Fasting duodenal juice and saliva were collected from 28 duodenal ulcer patients and 18 non-ulcer controls. IgA antibodies to herpes simplex virus type 1 [HSV-1] was- higher in duodenal juice and saliva from duodenal ulcer patients [32% and 46%] than those of non ulcer controls [22% and 39%]. The distribution of anti HSV-1 titer showed no marked difference between the two groups. The results need further studies to investigate whether HSV-1 is involved in the pathogenesis of peptic ulcer or not