Replacing Acid-Heat Precipitation with Sodium Dodecyl Sulphate Polyacrylamide Gel Electrophoresis Improves Detecting Bence-Jones proteinuria

Abdolfattah, Sarrafnejad; Mahasti Ghavami, Adel; Keyvan, Majidi; Maryam, Jalali; Sepideh, Nehzati; Mostafa, Gholamrezaei; Habib, Zafarmehr; Afshin, Namdar; Aliakbar, Amirzargar.

Archives of Medical Laboratory Sciences. 2015; 1 (3): 114-117

in English | IMEMR | ID: emr-186336

ABSTRACT

Background:

detecting Bence-Jones protein in urine is essential for determining plasma cell dyscrasia and multiple myeloma. Conventionally, acid-heat precipitation assay is used for detecting Bence-jones protein in most medical laboratories; however, because of the low accuracy of this test, other more sensitive tests like urine electrophoresis are recommended

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Index: IMEMR (Eastern Mediterranean) Language: English Journal: Arch. Med. Lab. Sci. Year: 2015

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Index: IMEMR (Eastern Mediterranean) Language: English Journal: Arch. Med. Lab. Sci. Year: 2015