Antimicrobial, antioxidant potential and phytochemical screening of Fagonia olivieri

ABSTRACT

The present paper investigates antioxidant, antimicrobial and photochemical screening different extracts of Fagonia olivieri. Analysis of the data indicated that the subject plant contained a good amount of flavonoids, tannins, saponins, terpenoids and steroids. Maximum concentrations of phenolic compounds was found in methanol fraction [29.0+/-6.12 mg GAE/g] while minimum [22.10+/-6.31mg GAE/g] in methylated spirit fraction. Similarly, ethanol fraction contained higher concentration of flavonoid content [135.4+/-7.63mg Quercetin/g] followed by methanol fraction [138.4+/-2.96 mg Quercetin/g]. Analysis of the data revealed that maximum antioxidant activity was recorded in mthylated spirit fraction [IC[50]= 10.69+/-1.66] followed by methanol fraction [IC[50]= 9.10+/-0.76] while no activity was noted in hexane fraction. The data indicated good antibacterial and antifungal activity against S. typhi, S. aureus, P. aeruginosa and A. flavus