Synthesis and characterization of PMBN as a biocompatible nanopolymer for bio-applications

ABSTRACT

Objective: Poly [2-methacryloyloxyethyl phosphoryl choline [MPC]-co-n-buthyl methacrylate [BMA]-co-p-nitrophenyl-oxycrabonyl poly ethylene glycol-methacrylate [MEONP]] [PMBN], a biocompatible terpolymer, is a unique polymer with applications that range from drug delivery systems [DDS] to scaffolds and biomedical devices. In this research, we have prepared a monomer of p-nitrophenyl-oxycarbonyl poly [ethylene glycol] methacrylate [MEONP] to synthesize this polymer. Next, we designed and prepared a smart, water soluble, amphiphilic PMBN polymer composed of MPC, BMA, and MEONP