Hippocampal expression of connexin36 and connexin43 during epileptogenesis in pilocarpine model of epilepsy
IBJ-Iranian Biomedical Journal. 2017; 21 (3): 167-173
in English
| IMEMR
| ID: emr-186954
ABSTRACT
Background:
Gap junctions [GJs] provide direct intercellular communications that are formed by hexameric protein subunits, called connexin [Cx]. The role of Cxs in epileptogenesis has not received sufficient attention. Hippocampus with critical function in epileptogenesis has a wide network of GJs. We examined the protein expression levels of hippocampal Cx36 [the prominent Cx present between GABAergic interneurons] and Cx43 [the main Cx expressed by astrocytes] during epileptogenesis in the pilocarpine model of epilepsy
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Index:
IMEMR (Eastern Mediterranean)
Language:
English
Journal:
Iran. Biomed. J.
Year:
2017
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