Autophagy knock down: as a booster for the replication of viruses in cell culture
Archives of Medical Laboratory Sciences. 2016; 2 (2): 62-66
in English
| IMEMR
| ID: emr-187152
ABSTRACT
Background:
Autophagy suppression recently has been known to have a remarkable effect for cellular adjustment and viability in the final stages of cancer. On the other hand, autophagy has the potential effect in preventing many viruses from replication. Beclin1 is the most substantial constituent in autophagy apparatus regulation. This study was intended to investigate the beclin1 siRNA knockdown effect on the extent of activity of the oncolytic vesicular stomatitis virus [VSV] as a model in cell culture
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Index:
IMEMR (Eastern Mediterranean)
Language:
English
Journal:
Arch. Med. Lab. Sci.
Year:
2016
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