Occult hepatitis B infection in Egyptian health care workers
EMHJ-Eastern Mediterranean Health Journal. 2017; 23 (5): 329-334
in English
| IMEMR
| ID: emr-187345
ABSTRACT
We tested the frequency of occult hepatitis B infection [OBI] among Egyptian healthcare workers [HCWs]. We tested 132 HCWs for hepatitis B virus [HBV] DNA by nested polymerase chain reaction [PCR], and hepatitis C virus antibody [anti-HCV] by ELISA. HCV RNA was measured by nested PCR in anti-HCV-positive HCWs. HBV-DNA-positive HCWs were subjected to HBV genotyping. We included 132 HCWs who were negative for hepatitis B surface antigen and positive for hepatitis B core antibody [anti-HBc]. OBI was detected in 7 male HCWs, and HBV E genotype was detected in 3, HBV D in 2 and HBV D and E in 2. Two OBI-positive HCWs had a history of neonatal hepatitis B vaccination. Anti-HCV seropositivity was detected in 17 HCWs who were positive for anti-HBc; 15 of whom were positive for HCV RNA by nested PCR. HCV infection was confirmed by anti-HCV and HCV RNA in 1 of 7 HCWs with OBI. In conclusion, Egyptian HCWs have a significant rate of OBI and HBV E genotype is prevalent
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Hepatitis B virus
/
Polymerase Chain Reaction
/
Cross-Sectional Studies
/
Hepatitis C
/
Hepatitis B Vaccines
/
Hepatitis C Antibodies
Type of study:
Prevalence study
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
English
Journal:
East Mediterr Health J.
Year:
2017
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