Amphotericin B induced hypokalemia in a diabetic patient with rhino-orbitocerebral mucormycosis
Anaesthesia, Pain and Intensive Care. 2017; 21 (1): 90-93
in English
| IMEMR
| ID: emr-187468
ABSTRACT
Rhino-orbito-cerebral mucormycosis is an aggressive and potentially lethal invasive fungal infection. Surgical debridement and amphotericin B remain the mainstay of treatment, however, associated side effects of amphotericin B like nephrotoxicity, hypokalemia, hypertension and arrhythmias need to be addressed. We discuss the anesthetic management of a 47 year old male with uncontrolled diabetes diagnosed with left sinoorbital mucormycosis posted for surgical debridement. The patient received amphotericin B and insulin preoperatively. Nephrotoxicity due to amphotericin B led to hypokalemia in this patient. We also discuss the role of liposomal formulation in preventing hypokalemia and other side effects associated with use of amphotericin
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Orbital Diseases
/
Nose Diseases
/
Central Nervous System Fungal Infections
/
Diabetes Complications
/
Hypokalemia
/
Mucormycosis
Type of study:
Case report
Limits:
Humans
/
Male
Language:
English
Journal:
Anaesth. Pain Intensive Care
Year:
2017
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