Detection mutations of JAK2 exon 12 in patients with JAK2 [v617f]-negative myeloproliferative disorders

S. Z., Makani; N., Parsamanesh; S., Mirzaahmadi; M., Hashemi; F. Shaveisi, Zadeh; N., Mansouri; M., Ghazi; M., Movafagh

S. Z., Makani; N., Parsamanesh; S., Mirzaahmadi; M., Hashemi; F. Shaveisi, Zadeh; N., Mansouri; M., Ghazi; M., Movafagh.

GJO-Gulf Journal of Oncology [The]. 2017; (24): 15-19

in English | IMEMR | ID: emr-187527

ABSTRACT

ABSTRACT

Background:

Mutations in exon 12 of JAK2 gene are detected as clonal markers in hematopoietic lineages in myeloproliferative disorders [MPNs]. Our aim was, to study the relation between N542E543del mutation of JAK2 gene and myeloproliferative neoplasms in V617F-negative patients

Subject(s)

Adult; Aged; Aged, 80 and over; Female; Humans; Male; Middle Aged; Mutation; Janus Kinase 2; Case-Control Studies

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Index: IMEMR (Eastern Mediterranean) Main subject: Case-Control Studies / Janus Kinase 2 / Mutation Limits: Adult / Aged / Female / Humans / Male Language: English Journal: Gulf J. Oncol. Year: 2017

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