Synergistic Effects of Arsenic Trioxide and Radiation: Triggering the Intrinsic Pathway of Apoptosis
IBJ-Iranian Biomedical Journal. 2017; 21 (5): 330-337
in English
| IMEMR
| ID: emr-188490
ABSTRACT
Background:
Arsenic trioxide [ATO] has been reported as an effective anti-cancer and a US Food and Drug Administration [FDA] approved drug for treatment of some cancers. The aim of this study was to determine the underlying apoptosis molecular and cellular mechanisms of ATO in the presence or absence of ionizing radiation [IR] in vitro in the glioblastoma multiforme [GBM] cell line, U87MG
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Oxides
/
Arsenicals
/
Radiation, Ionizing
/
In Vitro Techniques
/
Apoptosis
/
Glioblastoma
/
Cell Line, Tumor
Language:
English
Journal:
Iran. Biomed. J.
Year:
2017
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