Separation of n-substituted benzylidene-p-aminobenzoic acid conformers of biological activity

ABSTRACT

Several aldimines were produced by the reaction of p-aminobenzoic acid and certain substituted benzaldehydes. The products I-XII were resolved into their conformers via formation of solvates in a definite volume of appropriate solvent. The solvent differed in their volatility at room temperature. The structure of each compound was established by elemental analysis and IR, PMR spectral data. The antibacterial activities for all prepared compounds were examined