diagnostic utility of fibroindex in patients with chronic hepatitis C

ABSTRACT

Fibroindex was first described by Koda et as a simple, non invasive indirect marker of liver fibrosis, it was derived from the platelet count, AST, and gammaglobulin measurements. The aim'of the present study is to evaluate the fibrogenic marker Fibroindex as a non invasive marker of liver fibrosis in chronic hepatitis C and to correlate its serum levels with the stage of fibrosis assessed by histopathological staging of liver biopsy and virological characteristics including HCV RNA tilers. This study was carried out on 40 patients with evidence of chronic hepatitis C [positive HCV-Ab and positive HCV-RNA by PCR], they were [35] male and [5] female. All cases were selected from out patient clinic of the hepatology unit of research institute for tropical medicine [2011].the patients were had liver fibrosis from Fl to F4, Patients with no advanced liver fibrosis [Fl-F2] were considered as control. Fibroindex was calculated according to the equation described by related authors. [Fibroindex