[Effect of exogenous granulocyte colony-stimulating factor on ovulation and pregnancy rate in NMRI mice]

ABSTRACT

Background and Objective: Granulocyte colony-stimulating factors [G-CSF] and its receptor express in developing follicles, fetal and reproductive tissues. The serum G-CSF concentration significantly increases during the ovulatory phase in comparison with other phases, so G-CSF may have an important role in ovulation and the early cross-talk between mother and conceptus in both human and animal models. This study was done to evaluate the Effect of exogenous G-CSF on ovulation and pregnancy rate in NMRI mice