Enterolactone reduces telomerase activity and the level of its catalytic subunit in breast cancer cells

Davod, Ilbeigi; Mitra, Nourbakhsh; Shahnaz, Khaghani; Nahid, Einollahi; Nejat, Kheiripour; Zafar, Gholinejad; Mohammad, Alaee; Mostafa, Saberian

Davod, Ilbeigi; Mitra, Nourbakhsh; Shahnaz, Khaghani; Nahid, Einollahi; Nejat, Kheiripour; Zafar, Gholinejad; Mohammad, Alaee; Mostafa, Saberian.

Cell Journal [Yakhteh]. 2017; 19 (Supp. 1): 37-43

in English | IMEMR | ID: emr-189338

ABSTRACT

ABSTRACT

Objective:

There is a positive correlation between higher serum phytoestrogen concentrations and lower risk of breast cancer. The activation of telomerase is crucial for the growth of cancer cells; therefore, the aim of this study was to examine the effects of enterolactone [ENL] and enterodiol [END] on this enzyme

Subject(s)

Humans; Female; Lignans; Telomerase/drug effects; Catalytic Domain; Breast Neoplasms

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Index: IMEMR (Eastern Mediterranean) Main subject: Breast Neoplasms / Lignans / Telomerase / Catalytic Domain Limits: Female / Humans Language: English Journal: Cell J. [Yakhteh] Year: 2017

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