[Hypoglycemic interaction effects of 4 and 6 weeks swimming training and aloe barbadensis hydroalcoholic extract in streptozotocin induced diabetic rats]

Background: Exercise and nutrition are basic pillars of taking care and management of diabetes

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Objective: Aim of present study was to review the hypoglycemic interaction effects of swimming and Aloe barbadensis in diabetic rats

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Methods: 72 diabetic rats selected and divided in 9 groups [1] first week control, [2] fourth week control, [3] sixth week control, [4] 4 weeks Aloe barbadensis, [5] 6 weeks Aloe barbadensis, [6]4 weeks swimming, [7] 6 weeks swimming, [8] 4 weeks swimming with Aloe barbadensis, [9] 6 weeks swimming with Aloe barbadensis. For review the effect of diabetes induction 24 healthy rats selected and divided in 3 groups [10] first week control, [11] fourth week control and [12] sixth week control. Groups 6 and 8 swam for 4 weeks and rats of groups 7 and 9 swam for 6 weeks, 5 sessions per week and 30 minutes per session also groups 4, 5, 8 and 9 received 100 mg/kg Aloe barbadensis daily. For statistical analysis of data used one-way ANOVA, two-way ANOVA and bonferroni post hoc tests [P<0.05]

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Results: Diabetes induction has significant effect on increase of glucose and insulin resistance and reduction of insulin in diabetic rats [P<0.05], swimming training, Aloe barbadensis and combination of swimming and Aloe barbadensis have significant effect on reduction of glucose and insulin resistance [P<0.05] also 6 weeks swimming rather than 4 weeks and 6 weeks Aloe barbadensis rather than 4 weeks have more effect on reduction of glucose and insulin resistance [P<0.05]

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Conclusion: 4 and 6 weeks swimming and Aloe barbadensis have hypoglycemic interaction effects in diabetic rats