In vitro effects of wistar rat prenatal and postnatal cerebrospinal fluid on neural differentiation and proliferation of mesenchymal stromal cells derived from bone marrow
Cell Journal [Yakhteh]. 2018; 19 (4): 537-544
in English
| IMEMR
| ID: emr-189843
ABSTRACT
Objective:
cerebrospinal fluid [CSF] plays an important role in cortical development during the fetal stages. Embryonic CSF [E-CSF] consists of numerous neurotrophic and growth factors that regulate neurogenesis, differentiation, and proliferation. Mesenchymal stem cells [MSCs] are multi-potential stem cells that can differentiate into mesenchymal and non-mesenchymal cells, including neural cells. This study evaluates the prenatal and postnatal effects of CSF on proliferation and neural differentiation of bone marrow MSCs [BM-MSCs] at gestational ages E19, E20, and the first day after birth [P1]
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Index:
IMEMR (Eastern Mediterranean)
Language:
English
Journal:
Cell J. [Yakhteh]
Year:
2018
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