role of serum adiponectin levels in women with polycystic ovarian syndrome

ABSTRACT

Background: adiponectin is a recently identified adipocyte-derived collagen-like protein. In humans, adiponectin levels were found to be decreased in obese, compared to normal individuals, whereas high adiponectin levels are independently associated with increased insulin sensitivity. The specific role of adiponectin in these metabolic conditions is not clear it may have a causative role, or it could be regulated by insulin and serve as a marker for insulin resistance. Adiponectin levels hold great promise for use in clinical applications as a potent indicator of underlying metabolic complications