Plasmapheresis: an effective treatment in patients of toxic epidermal necrolysis: case report of two patients

ABSTRACT

Toxic epidermal necrolysis [TEN] is an acute, life-threatening cutaneous drug reaction that predominantly involves the skin and mucous membranes. It is a rare disorder and treated as a medical emergency, due to its fatal outcome. The principles of management include immediate removal of culprit drug[s], supportive management and specific drug therapies or procedures, of which plasmapheresis is one treatment modality. We report two patients of TEN, being successfully treated with plasmapheresis, proving it to be a life saving treatment modality