Helicobacter pylori infection: independent risk indicator of gastric adenocarcinoma and the role of surgery

ABSTRACT

Background: Helicobacter pylori is a ubiquitous organism that is current in about half of the global population. Chronic infection with helicobacter pylori causes atrophic and even metaplastic changes in the stomach, and it has a known association with peptic ulcer disease. This bacterial species colonizes the stomach of the greater part of the total populace; notwithstanding, only a very small proportion of infected subjects improve adenocarcinoma. helicobacter pylori causes a chronic gastritis that might last periods, and a multistep precancerous process is documented for the most common histologic type of gastric adenocarcinoma the intestinal type