N-acetylcysteine compared to metformin, improves the expression profile of growth differentiation factor-9 and receptor tyrosine kinase c-kit in the oocytes of patients with polycystic ovarian syndrome
IJFS-International Journal of Fertility and Sterility. 2018; 11 (4): 270-278
in English
| IMEMR
| ID: emr-191359
ABSTRACT
Background:
Paracrine disruption of growth factors in women with polycystic ovarian syndrome [PCOS] results in production of low quality oocyte, especially following ovulation induction. The aim of this study was to investigate the effects of metformin [MET], N-acetylcysteine [NAC] and their combination on the hormonal levels and expression profile of GDF-9, BMP-15 and c-kit, as hallmarks of oocyte quality, in PCOS patients
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Index:
IMEMR (Eastern Mediterranean)
Type of study:
Controlled clinical trial
Language:
English
Journal:
Int. J. Fertil. Steril.
Year:
2018
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