Predicting recurrence in Ta – T1 bladder tumors using EORTC risk tables

ABSTRACT

Background: Studies of European Organization for Research and Treatment of Cancer are very important; they have designed risk tables and score depending on clinical and pathologic features of the tumor. Purpose: Identifying the concordance of EORTC criterions in bladder tumors in our patients by studying recurrence rate and its accordance with the similar studies of EORTC. Material and Methods: A retrospective study contains all superficial bladder tumors patients treated by TURBT at Al Assad University Hospital during 2003-2004, to identify the recurrent cases by using EORTC criterions, The patient`s files were analyzed for 5 years. There were 114 patients, 109 males and 5 females, 80 of them were younger than70 years old. The patients were classified according to tumors number, size, prior recurrence rate, grade, stage and presence of CIS complex. We have calculated Recurrence probabilities according to EORTC system, points concerning this score and real recurrence rate. Results: 48.1% have single tumor, 47% have 2-7 lesions. 77.9% have tumor less than 3 cm. 47.7% were primary tumors. 82.6% of these tumors were T1 and 17.4% were Ta. 67.1% of them were G2. CIS was found in 2.7% of patients. There were 56 patients with 1-4 points, 75 with 5-9 points and 17 with 10-17 points. Real recurrence rate after one year of TURBT was 25-70.6% and 44.6-94.1% after 5 years. There was a concordance between our study and EORTC studies in the patients of 1-9 points on EORTC score, our patients of 10-17 points have a larger recurrence rate. Conclusion: EORTC score is suitable to predict recurrence in superficial bladder tumors, and can be used in every patient, interval between periodic cystoscopies with patients of high score should not be long because recurrence probabilities increase with time