Therapeutic effects of laparotomy and laparoscopic surgery on patients with gastric cancer

ABSTRACT

Objective: To compare the therapeutic effects of laparotomy and laparoscopic surgery on patients with gastric cancer. Methods: Sixty-six patients with gastric cancer who were treated in our hospital from January 2012 to December 2013 were selected and divided into a control group and an observation group by the random number method [n=33]. The control group was treated by traditional laparotomy, and the observation group was treated by laparoscopic surgery. CD4 /CD8 ratios and IgG expressions in the patients were detected on preoperative and postoperative fourth days. Intraoperative blood loss, surgical time, time of anal gas evacuation and time of postoperative independent ambulation of the two groups were observed. Results: The intraoperative blood loss, surgical time, time of anal gas evacuation, time of postoperative independent ambulation, time of urinary catheter indwelling and average hospitalization stay length of the observation group were significantly different from those of the control group [P<0.05]. The postoperative rates of fever and complications in the observation group were significantly lower than those of the control group, and the two groups had significantly different CD4 /CD8 ratios and IgG levels on the postoperative 4th day [P<0.05]. Conclusion: Compared with traditional laparotomy, laparoscopic surgery can well treat patients with gastric cancer minimally invasively. Meanwhile, their postoperative recovery was facilitated due to slightly affected humoral immunity and cellular immune function