Targeting colorectal cancer cell lines using nanobodies; AgSK1as a potential target
IJB-Iranian Journal of Biotechnology. 2017; 15 (2): 78-86
in English
| IMEMR
| ID: emr-192445
ABSTRACT
Background:
Colorectal cancer is the third most common type of aggressive cancers. Chemotherapy, surgery, and radiotherapy are the common therapeutic options for treating this cancer. Due to the adverse side-effects of these methods, immunotherapy is considered as an appropriate alternative therapeutic option. Treatment through the application of monoclonal antibodies is considered as a novel alternative therapeutic method for cancers. The variable fragments of the antibodies' heavy chain or VHHs have a wide application in molecular biology and biotechnology. VHHs are compatible with the phage display technology which allows rapid and high throughput screening for antibodies isolation
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Research
/
Cell Line, Tumor
/
Single-Domain Antibodies
/
Immunotherapy
Limits:
Animals
/
Humans
Language:
English
Journal:
Iran. J. Biotechnol.
Year:
2017
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