Detection of methicillin resistant staphylococcus aureus with reduced susceptibility to vancomycin

ABSTRACT

Background: As there is no molecular-based assays available for the detection of hVISA and VISA. However, increasing amounts of data support a number of methods for the screening and confirmation of heterogeneous vancomycin intermediate S. aureus [hVISA] and vancomycin intermediate S. aureus [VISA] infection. The vancomycin MIC result alone is unable to accurately distinguish hVISA from VSSA isolates, and the use of MIC testing alone will fail to detect h VISA strains that are relatively common among isolates of Staphylococcus aureus [S. aureus] with broth MICs of 2g per ml. of Staphlococcus aureus [S. aureus] with broth MICs of 2 g per ml