Evaluation of factors affecting size and size distribution of chitosan-electrosprayed nanoparticles

ABSTRACT

Background: Size and size distribution of polymeric nanoparticles have important effect on their properties for pharmaceutical application. In this study, Chitosan nanoparticles were prepared by electrospray method [electrohydrodynamic atomization] and parameters that simultaneously affect size and/or size distribution of chitosan nanoparticles were optimized