Congenital abnormality effect of methamphetamine on histological, cellular and chromosomal defects in fetal mice

ABSTRACT

Background: methamphetamine [MA] is a potent psychomotor stimulant with high abuse and addictive potential. MA is a neurotoxic drug which is widely abused by females of childbearing age, raising serious public health concerns in terms of exposure of the fetus to the drug. Neurotoxic effects of MA on adult are well known, such as dopaminergic nerve terminal degeneration and cell death in regions of brain in some doses