value of electron microscopy in the diagnosis of Non-Hodgkin's Lymphoma

ABSTRACT

Fifteen patients presented with non-Hodgkin's lymphoma [NHL] were subjected to complete history taking and clinical examination, radiological studies and microscopic examination of lymph node biopsy. The most recent histopathological classification used is the Working Formulation. Recently, electron microscopy [EM] is used for better diagnosis and prognosis of malignant lymphoma. It was found that low grade lymphoma accounted for 13.33% by light microscopy [LM]. It shifted to the higher percentage [26.67] by EM. While, the high grade lymphoma accounted for 40% by light microscopy. It shifted to a lower percentage [20%] by EM. Although this type of investigation is expensive, it is very important in equivocal cases for the accurate diagnosis of NHL