Comparison between liver biopsy and hyaluronic acid in chronic liver disease

ABSTRACT

Background: CLD is considered a major cause of mortality throughout the world including south Asia. The clinical examination is often unreliable in assessing the severity of disease. Liver biopsy [LB] is the gold standard for assessing CLD but it is invasive, painful and has complications and technical problems. Hyaluronic acid [HA], an ideal marker of fibrosi, it has a high degree of sensitivity and specificity and is a simple laboratory test detecting fibrosis in CLD patients