Breast cancer: genetics, risk factors, molecular pathology and treatment

ABSTRACT

Breast cancer within incident of one million new cases each year has become one of the most common malignancies and leading cause of death among females. This disease is comprised of about 18% of women cancers. The availability of early detection and improved treatments may decrease the mortality rates which reflected in the United States and many other western countries. Breast cancer in over the past 20 years may also have contributed to the Increasing age, nulliparity, positive family history of breast cancer, and use of menopausal hormone therapy were positively risk factors associated with breast cancer. Therefore, studying this malignity is prominent due to its mortality world wild. Evaluation and study of different aspects of breast cancer have been established during past decays which, in this review, it is presented and discussed