Bacteriophage as a novel antibacterial agent in industry and medicine

ABSTRACT

Bacteriophage is a kind of virus that infect bacteria, and is distinct from the animal and plant viruses that could have either lytic or lysogenic cycle. Lytic phages known as candidates for phage therapy, since they rapidly replicate into their host and lyse them. Theoretically, phages have more than a few benefits over routine antibiotics. They are extremely specific and for their targeted hosts and also are safe for human, because they have no activity against eukaryote cells. Over this time, phages were used to treat various infections. Although, phages have a lot of advantages against antibiotics, their industrial production as a commercial production have been ceased in most of the western European countries. These days, by raising of antibiotics resistance and inefficiency of antibiotic to overcome bacteria biofilm, there is renewed global attention in phage applications as a potentially powerful antibacterial agents. Different published paper through the world indicates bacteriophage could be recruited as suitable agent for therapeutic purposes in medicine and food industry. Therefore, here we tried to review most of these ideas about phage application as a rapid review