First report on the Co-inheritance of beta-globin IVS-I-5 [G-C] thalassemia with delta globin CD12 [Asn-Lys [AAT-AAA]] hba2- NYU in Iran

ABSTRACT

Background: co-inheritance of beta- and delta-globin mutations in Iran is not uncommon. This situation may interfere with correct diagnosis and genetic counseling of alpha- and beta-thalassemia in screening programs. Here we report the co-inheritance of beta- and delta-globin gene mutations in an individual with microcytosis, hypochromia and a normal hemoglobin A2 [HbA2] level