Contribution of outer membrane protein of pseudomonas aeruginosa to fluoroquinolones resistance

ABSTRACT

Background and aim of work Pseudomonas aeruginosa is an important opportunistic pathogen infects immunocompromised hosts and characterized by its natural resistance to a variety of antimicrobial agents, especially fluoroquinolones. The purpose of this study was the assessment of the fluoroquinolones resistance level among P. aeruginosa clinical isolates, furthermore to compare between the outer membrane protein profile of flouroquinolones susceptible and resistant isolates of P. aeruginosa using Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis [SDS-PAGE] technique