[Effect of lithium on neuropathic pain induced by partial ligation of rat sciatic nerve]

ABSTRACT

Background: Neuropathic pain is a type of chronic pain resulting from injury to the peripheral or central nervous system. Moreover, lithium is the main medication used to treat bipolar [manic-depression] disorder and some recent studies have also confirmed the neuroprotective effects of lithium. Considering the most common cause of neuropathic pain, nerve injury, the present study was designed to evaluate the effect of lithium on neuropathic pain induced by partial ligation of sciatic nerve in rat