effect of hepatic insufficiency due to cholestasis on teeth and surrounding structure in albino rats [a histological study]

ABSTRACT

A recent innovation in dentistry is the preparation and use of platelet rich plasma [PRP] , a concentrated suspension of the growth factors found in the platelets. These growth factors are involved in implant wound healing and are postulated as promoters of bone regeneration. The current study was performed to evaluate the effect of PRP added to resorbable deantigenic bone tissue of equine origin on bone regeneration in dehiscence defects around immediate dental implants. Twelve implants were installed in the incisor, canine and premolar regions immediately following tooth extraction. The peri-implant defects were augmented with a composite graft of autologus PRP and a xeno graft [in a ratio of 11] and protected by collagen membrane. The dimensions of the peri-implant defects and the bucco-lingual width of the alveolar ridge were measured at baseline and 6 months after healing during second stage surgery for abutment connection. The ridge width showed a decrease from 7.1mm to 6.3 mm after 6 months healing. The deepest [7.6mm] and widest [2.7mm] defects were located on the buccal aspect .Six months after healing no residual defect could be probed around the installed implants