Study of carbon nanotubes effects on the chondrogenesis of human adipose derived stem cells in alginate scaffold

ABSTRACT

Background: Osteoarthritis is one of the most common diseases in middle-aged populations in the World and could become the fourth principal cause of disability by the year 2020. One of the critical properties for cartilage tissue engineering [TE] is the ability of scaffolds to closely mimic the extracellular matrix and bond to the host tissue. Therefore, TE has been presented as a technique to introduce the best combination of cells and biomaterial scaffold and to stimulate growth factors to produce a cartilage tissue resembling natural articular cartilage. The aim of study is to improve differentiation of adipose derived stem cells [ADSCs] into chondrocytes in order to provide a safe and modern treatment for patients suffering from cartilage damages