Drug-induced linear IgA bullous dermatosis simulating toxic epidermal necrolysis

ABSTRACT

Linear IgA bullous dermatosis [LAD] is an autoimmune subepidermal blistering disorder. LAD may be either idiopathic or drug related; the most common drug being vancomycin. The clinical presentations of both idiopathic and drug-related LAD are variable and may mimic other blistering disorders. We report a case of a 76-year-old man known to have a renal cell carcinoma who presented a vancomycin-induced LAD that clinically mimicked toxic epidermal necrolysis [TEN]