Reactions with alpha-substituted cinnamonitriles: synthesis of benzo [h] quinolines and naphthol [1,2, b] pyrans
Egyptian Journal of Pharmaceutical Sciences. 1991; 32 (3-4): 827-834
in English
| IMEMR
| ID: emr-19741
ABSTRACT
Alpha-substituted cinnamonitrile derivatives [1a-i] reacted with alpha-tetralone [2] in the presence of ammonium acetate to yield 5, 6-dihydrobenzo [h] quinoline derivatives with different substituents at 2,3, and 4 positions [3,7-9]. Substituting sodium acetate for ammonium acetate led to the formation of the 5, 6-dihydro-2-imino-4-phenylnaphtho [1, 2-b] pyran-3-carbonitrile [5]
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Pyrans
/
Quinolines
/
Drug Compounding
Language:
English
Journal:
Egypt. J. Pharm. Sci.
Year:
1991
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