Synthesis and biological activity of certain antipyrine derivatives
Egyptian Journal of Pharmaceutical Sciences. 1991; 32 (3-4): 529-542
in English
| IMEMR
| ID: emr-19749
ABSTRACT
4-hydroxyantipyrine 2 reacted with different 2-chloroacetonilides to give the corresponding antipyrinyl ethers 3. Also, 4-chloro acetylaminoantipyrin 4 treated with the potassium salt of some nonsteroidal antiinflammatory acids, the potassium salt of certain ureido acids and some hydroxylated compounds afforded compounds 5, 7 and 9, respectively. The structure of the products was confirmed by microanalysis and spectral data. Preliminary pharmacological testing showed that some of these new products have demonstrated analgetic antiinflammatory effects
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Drug Compounding
Language:
English
Journal:
Egypt. J. Pharm. Sci.
Year:
1991
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