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Identification of an mtDNA setpoint associated with highest levels of CD44 positivity and chemoresistance in HGC-27 and MKN-45 gastric cancer cell lines
Cell Journal [Yakhteh]. 2018; 20 (3): 312-317
in English | IMEMR | ID: emr-197608
ABSTRACT

Objective:

Cancer stem cells [CSCs] have important roles in survival and chemoresistance. These cells are commonly recognized with CD44 and CD24 markers. In this study, we aimed to analyze the effects of mtDNA content on cell surface positivity for anti-CD24 and anti-CD44 antibodies and chemoresistance level in AGS, HGC-27 and MKN-45 gastric cancer [GC] cell lines and to determine a setpoint for mtDNA copy for each cell line
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Index: IMEMR (Eastern Mediterranean) Language: English Journal: Cell J. [Yakhteh] Year: 2018

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Index: IMEMR (Eastern Mediterranean) Language: English Journal: Cell J. [Yakhteh] Year: 2018