Morphological, ultrastructural, and molecular aspects of in vitro mouse embryo implantation on human endometrial mesenchymal stromal cells in the presence of steroid hormones as an implantation model

ABSTRACT

Objective: This experimental study aimed to evaluate the effects of 17beta-estradiol [E2] and progesterone [P4] on the interaction between mouse embryo and human endometrial mesenchymal stromal cells, and gene expressions related to implantation [alphaV and beta3 integrins, interleukin-1 receptor [IL-1R], and leukemia inhibitory factor receptor [LIFR]] using an in vitro twodimensional model