Diabetes mellitus: its epidemiology and pathogenesis: a global focus on type 2

ABSTRACT

Diabetes mellitus enjoys pandemic status. Majority of patients will suffer, life threatening complications resulting from microvascular and macrovascular damage associated with diabetic nephropathy, cardiovascular and cerebrovascular disease, dyslipidemias and a plethora of intracellular and extracellular biochemical abnormalities. New theories regarding its pathogenesis and specially those for type 2 have emerged over the years. This review focuses on the different aspects of epidemiology, pathogenesis and presentations of type 2 diabetes mellitus