Utility of routine gall bladder histopathology after living donor hepatectomy in liver transplantation

ABSTRACT

Intraoperative cholangiogram with cholecystectomy is a routinely performed procedure in living donor liver transplantation [LDLT].The objective of this study was to determine the frequency of gall bladder pathology in healthy living donors and whether routine histopathology can be omitted. This was a retrospective review of 366 donors who underwent donor hepatectomy between 2012 and 2016. Primary outcome of interest was frequency of abnormal histopathology findings in removed gall bladder specimen; and if their distribution was different with respect to gender, age and BMI. Male to female ratio was 2.11. Median age was 26 [18-50] years. Median BMI was 23.9 [15.7-35] Kg/m2. The most common finding was chronic cholecystitis in 189 [51.6%]. Gall bladder pathology was more frequently seen in donors with BMI >25 Kg/m2