OX40 gene and serum protein expression profiles in patients with Parkinson's disease

ABSTRACT

Objective: Inflammation of the immune system and the central nervous system has been known as an important predisposing factor for Parkinson's disease [PD]. Increased expression of OX40 protein [CD134] is a known factor for increased inflammation and initiation of NF-kappa-B signaling pathway in different diseases. We aimed to investigate the expression of OX40 at the transcript and serum protein levels