Comparative study between sublingual and vaginal misoprostol for induction of labor in post term pregnant patients with unfavourable cervix

ABSTRACT

Background: Pharmacological studies suggest that sublingual route might be the optimal route of administration for PGE1 analogue misoprostol because the avoidance of the first pass hepatic circulation would yield bioavailability like that achieved with the vaginal route along with an earlier onset of action and a prolonged activity