Histopathological effects of titanium dioxide nanoparticles and the possible protective role of N-Acetylcysteine on the testes of male albino rats

ABSTRACT

Background: Titanium dioxide [TiO2] is a white pigment which is used in paints, plastics, etc. It is reported that TiO2 induces oxidative stress and DNA damage. N-acetylcysteine [NAC] has been used to fight oxidative stress-induced damage in different tissues. The objective of this study was to evaluate the toxic effects of orally administered TiO2 nanoparticles and the possible protective effect of NAC on the testes of adult male albino rats