Therapeutic effect of chlorpheniramine in treatingupper airway cough syndrome [UACS] and chronic rhinitis/sinusitis

ABSTRACT

This paper aims to analyze the specific effect of chloropheniramine on upper airway cough syndrome is related to its treatment of chronic rhinitis and sinusitis. A total of 218 patients admitted to hospital between March 2014 and June 2016 were treated with chlorpheniramine. The patients were divided into two groups based on treatment effect in follow-up visits [all were effective] effective group [114 cases, 52.29%] and ineffective group [104 cases, 47.71%]. The proportion of complicated rhinitis or sinusitis of the two groups were compared, and improvement effect on clinical symptoms of chronic rhinitis and sinusitis after treatment was compared. The probability of rhinitis / sinusitis was 65.79% [75/114] in the effective group and 69.23% [72/104] in the ineffective group. There was no statistical difference between the two groups [P>0.05]. In both effective and ineffective group, the symptoms such as chest tightness and shortness of breath and pharyngeal discomfort were improved to a certain extent, and the effective group had better improvement effect, but there was no statistical difference between the two groups [P>0.05] In addition, there was no correlation between improvment of cough and improvement of symptoms in the effective group, 21 cases of cough disappeared complete disappearance rate of other symptoms was only 57.15% [12/21]. Chlorpheniramine is effective to some extent in treatment of upper airway cough syndrome, but chlorpheniramine in treatment of upper airway cough syndrome is not associated with rhinitis/sinusitis treatment