Postoperative pain management after impacted third molar surgery with preoperative oral lamotrigine, a Randomized, Double-blind, placebo-controlled Trial

ABSTRACT

Statement of the Problem: Extraction of the impacted third molar is often associat-ed with severe postoperative pains, management of which are a big challenge. Lamotrigine is a new antiepileptic drug with pre-emptive analgesic properties, which is hypothesized to alleviate postoperative pain